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Validation of fetal DNA fraction estimation and its application in noninvasive prenatal testing for aneuploidy detection in multiple pregnancies |
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| Authors: | Min Chen Fuman Jiang Yulai Guo Huanchen Yan Jiayan Wang Longmei Zhang XiaoJing Zeng Sheng Li Yufan Li Nan Li Chunsheng Zhang Wentao Zhu Bole Du Yang Wang Zhiheng Lan Xingcheng Luo Fei Luo Dunjin Chen |
| Affiliation: | 1. Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;2. School of Automation Science and Engineering, South China University of Technology, Guangzhou, China Guangzhou Jingke Medical Laboratory, Guangzhou, China Shenzhen Jingke Genetic Science and Technology Co., Ltd., Shenzhen, China;3. Guangzhou Jingke Medical Laboratory, Guangzhou, China;4. Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Obstetrics & Gynecology Institute of Guangzhou, Guangzhou, China The Medical Centre for Critical Pregnant Women in Guangzhou, Guangzhou, China Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou, China Key Laboratory for Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou, China;5. School of Automation Science and Engineering, South China University of Technology, Guangzhou, China;6. Obstetrics & Gynecology Institute of Guangzhou, Guangzhou, China |
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