| 钐对小鼠睾丸组织超微结构的影响 |
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| 引用本文： | 杨三平,申秀英,吴益,赵倩,阮琴.钐对小鼠睾丸组织超微结构的影响[J].中国环境科学,2011,31(11):1896-1899. |
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| 作者姓名： | 杨三平 申秀英 吴益 赵倩 阮琴 |
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| 作者单位： | 1. 浙江师范大学化学与生命科学学院,浙江金华,321004
2. 浙江科技学院生物与化学工程学院,浙江杭州,310023 |
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| 基金项目： | 浙江省教育厅项目，浙江省自然科学基金 |
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| 摘 要： | 为评价稀土元素钐对雄性小鼠睾丸组织结构的影响,将小鼠分组,并饮用含硝酸钐0、5、50、500、2000mg/L的蒸馏水,90d后处死,称量体重和睾丸重量,制备光镜和电镜切片.结果表明,与对照组相比,2000mg/L剂量组的小鼠睾丸脏器系数显著降低;光镜观察显示高剂量组的小鼠睾丸曲细精管萎缩、变性，结构紊乱,生精细胞明显减少;电镜观察显示高剂量的钐可致曲细精管管膜萎缩,各级生精细胞均受到不同程度的损伤,线粒体普遍出现肿胀、空泡化现象,核膜模糊或缺失,染色质边集.提示500,2000mg/L剂量下的钐暴露对小鼠的睾丸组织具有一定的损伤效应.
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| 关 键 词： | 稀土元素 钐 睾丸 超微结构 |
| 收稿时间： | 2011-03-01; |
Effects of sub-chronic samarium exposure on ultra-structure of mice testis |
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| YANG San-ping,SHEN Xiu-ying,WU Yi,ZHAO Qian,RUAN Qin.Effects of sub-chronic samarium exposure on ultra-structure of mice testis[J].China Environmental Science,2011,31(11):1896-1899. |
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| Authors: | YANG San-ping SHEN Xiu-ying WU Yi ZHAO Qian RUAN Qin |
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| Institution: | YANG San-ping1,SHEN Xiu-ying2,WU Yi1,ZHAO Qian1,RUAN Qin1(1.College of Chemistry and Life Sciences,Zhejiang Normal University,Jinhua 321004,China,2.College of Biology and Chemical Engineering,Zhejiang University of Science and Technology,Hangzhou 310023,China) |
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| Abstract: | In order to evaluate the sub-chronic toxicity of rare earth element samarium on testis of male mice,the mice were randomly selected and exposed to drinking water containing 0,5,50,500,2000mg/L of samarium nitrate for 90d.At the end of treatment,the mice were weighed and euthanized,and the organ coefficients were determined.The histopathology and electron microscopy observations were evaluated as well.Compared with the control group,the organ coefficient of testis from 2000mg/L group was significantly decrea... |
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| Keywords: | rare earth element samarium testis ultra-structure |
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