Organohalogen contaminants and metabolites in cerebrospinal fluid and cerebellum gray matter in short-beaked common dolphins and Atlantic white-sided dolphins from the western North Atlantic |
| |
| Authors: | Eric W Montie Christopher M Reddy Wouter A Gebbink Katie E Touhey Mark E Hahn Robert J Letcher |
| |
| Institution: | 1. Littoral Environment et Sociétes (LIENSs), UMRi 7266 CNRS-Université de La Rochelle, 2 Rue Olympe de Gouges, 17042 La Rochelle Cedex 01, France;2. Coordinadora para o Estudo dos Mamiferos Mariños (CEMMA), Apdo. 15, Pontevedra 36380, Spain;3. Centro de Biologia Molecuar e Ambiental (CBMA)/Sociedade Portuguesa de Vida Selvagem (SPVS), Dep. de Biologia, Universidade do Minho, Campus de Gualtar, Braga 4710-057, Portugal;4. Marine Scotland, Marine Laboratory, Victoria Road, Aberdeen AB11 9DB, United Kingdom;5. Instituto de Investigaciones Marinas (C.S.I.C), Eduardo Cabello 6, 36208 Vigo, Spain;6. Oceanlab, University of Aberdeen Main Street, Newburgh, Aberdeenshire AB41 6AA, United Kingdom;7. Centre for Environmental and Marine Studies (CESAM), Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal;8. Instituto Español de Oceanografía, Centro Oceanográfico de Vigo, P.O. Box 1552, Vigo 36200, Spain;9. Marine Mammal Research Unit, Fisheries Centre, University of British Columbia, 2202 Main Mall, Vancouver, British Columbia V6T 1Z4, Canada;1. Departamento de Química, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rua Marquês de São Vicente, 225, Gávea - Rio de Janeiro, RJ 22453-900, Brazil;2. Instituto Oswaldo Cruz/Fiocruz, Av. Brasil 4.365, Manguinhos, Rio de Janeiro, RJ 21040-900, Brazil;3. Instituto Oceanográfico, Universidade de São Paulo (USP), Praça do Oceanográfico 191, Butantã, São Paulo, SP 05508-900, Brazil;4. Systems Ecology, Leibniz Center for Tropical Marine Ecology (ZMT), Fahrenheitstrasse 6, 28359, Bremen, Germany;5. Institute for Occupational and Social Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, D-52074 Aachen, Germany;1. Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway;2. Environment Agency, Traðagøta 38, P.O. BOX 2048, FO-165 Argir, Faroe Islands;3. Ecotoxicology and Wildlife Health Division, Environment Canada, National Wildlife Research Centre, 1125 Colonel By Dr. (Raven Road), Carleton University, Ottawa K1A 0H3, Canada;4. Age Dynamics, Huldbergs Allé 42, DK-2800 Kongens Lyngby, Denmark |
| |
| Abstract: | Concentrations of several congeners and classes of organohalogen contaminants (OHCs) and/or their metabolites, namely organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs), hydroxylated-PCBs (OH-PCBs), methylsulfonyl-PCBs (MeSO2-PCBs), polybrominated diphenyl ether (PBDE) flame retardants, and OH-PBDEs, were measured in cerebrospinal fluid (CSF) of short-beaked common dolphins (n = 2), Atlantic white-sided dolphins (n = 8), and gray seal (n = 1) from the western North Atlantic. In three Atlantic white-sided dolphins, cerebellum gray matter (GM) was also analyzed. The levels of OCs, PCBs, MeSO2-PCBs, PBDEs, and OH-PBDEs in cerebellum GM were higher than the concentrations in CSF. 4-OH-2,3,3′,4′,5-pentachlorobiphenyl (4-OH-CB107) was the only detectable OH-PCB congener present in CSF. The sum (Σ) OH-PCBs/Σ PCB concentration ratio in CSF was approximately two to three orders of magnitude greater than the ratio in cerebellum GM for dolphins. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
