In Vitro Cytotoxicity of Amylose-Based Bioplastic for Packaging Applications |
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| Authors: | Sanchita Bandyopadhyay-Ghosh Robert Jeng Joydeep Mukherjee Mohini Sain |
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| Institution: | (1) Centre for Biocomposites and Biomaterials Processing, University of Toronto, 33 Willcocks Street, Toronto, ON, M5S 3B3, Canada;(2) The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, University of Toronto, 101 College Street, Toronto, ON, M5G 1L7, Canada |
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| Abstract: | Amylose containing polysaccharides are one of the most abundant and inexpensive naturally occurring biopolymers. Therefore,
they are one of the most promising candidates to produce substitute plastics, especially in packaging applications. To determine
the suitability for packaging applications, cytotoxicity of a modified amylose based bioplastic was investigated using NIH
3T3 Fibroblast cells from observation of cell morphology and MTS assay. Chemical durability of the amylose based bioplastic
film was also studied by ion release and pH measurement after immersing the film into water. In vitro cytotoxicity (Cell morphology
study and MTS assay) showed that the amylose based bioplastic film has in vitro biocompatibility and can be used for packaging
applications. The ion release and pH measurement also supported the results. |
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