| 微囊藻毒素诱导细胞氧化胁迫的研究进展(Progress in Oxidative Stress on Cell Induced by Microcystin) |
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| 引用本文： | 朱枫,钱晨,卢彦.微囊藻毒素诱导细胞氧化胁迫的研究进展(Progress in Oxidative Stress on Cell Induced by Microcystin)[J].生态毒理学报,2010,5(6):769-775. |
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| 作者姓名： | 朱枫 钱晨 卢彦 |
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| 作者单位： | 南京大学生命科学学院,医药生物技术国家重点实验室,南京,210093 |
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| 基金项目： | 国家重点基础研究发展计划（No. 2008CB418102）；教育部科学技术研究重点项目（No. 107049） |
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| 摘 要： | 微囊藻毒素对生物机体具有强烈的毒性.近几年的研究表明,微囊藻毒素能够诱导细胞产生氧化胁迫,这可能是微囊藻毒素的致毒机理的一个重要方面.在总结国内外相关研究基础上,论文从微囊藻毒素诱导细胞氧化损伤以及影响其抗氧化防御系统两个方面综述了微囊藻毒素诱导细胞氧化应激的研究进展.
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| 关 键 词： | 微囊藻毒素 氧化胁迫 致毒机理 抗氧化防御系 细胞氧化损伤 |
| 收稿时间： | 1/8/2010 12:00:00 AM |
| 修稿时间： | 2010/6/11 0:00:00 |
Progress in Oxidative Stress on Cell Induced by Microcystin |
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| ZHU Feng,QIAN Chen and LU Yan.Progress in Oxidative Stress on Cell Induced by Microcystin[J].Asian Journal of Ecotoxicology,2010,5(6):769-775. |
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| Authors: | ZHU Feng QIAN Chen and LU Yan |
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| Institution: | ZHU Feng,QIAN Chen,LU Yan Department of Life Science,Nanjing University,Nanjing 210093 |
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| Abstract: | Cyanobacteria Blooms give rise to releases of large quantity of Microcystisn, which is highly toxic to the organisms. Recent researches show that microcystin induces cells to produce the oxidative stress which may be the mechanism of toxicity of microcystin. In this paper, the microcystin inducing cells to produce the oxidative stress have been summarized in two parts: The oxidative damage of microcystin on cell and its effects on the anti-oxidative system. |
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| Keywords: | microcystins oxidative stress mechanism of toxicity anti-oxidative system oxidative damage |
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