我国青霉素钾盐特征VOCs的挥发损失估算

针对我国典型制药行业--青霉素钾盐生产工艺过程中,特征VOCs的排污节点分析,利用大量调研数据、物料衡算和经验公式,估算了生产每吨青霉素钾盐各排污节点VOCs的挥发量,结合我国近年来青霉素钾盐产量情况,估算出其总排放量.结果表明,在青霉素钾盐生产过程中,特征VOCs为醋酸丁酯和丁醇,主要产生在提取阶段、精制阶段以及储罐呼吸过程中,并且在我国,生产单位质量青霉素钾盐醋酸丁酯和丁醇的挥发量大约为20.49kg/t和12.93kg/t.该研究可为制药行业青霉素钾盐生产工艺过程中VOCs的管理与控制提供科学依据.

Estimation of the volatilization amount of typical VOCs for production of potassium penicillin salt in China

Volatilization amount of typical VOCs for the production potassium penicillin salt per ton in China is estimated on the basis of emission nodes analysis, investigate data, and empiric formulas. According to the total production of potassium penicillin salt in China in recent years, the total volatilization of VOCs is also suggested. It shows that the typical VOCs are butyl acetate and butanol for the production potassium penicillin salt, which are mainly discharged from extraction, refining and tank breathing process. The volatilization of butyl acetate and butanol are about 20.49kg/t and 12.93kg/t respectively for one ton potassium penicillin salt. In recent years, the annual typical VOCs volatilization of potassium penicillin salt is becoming greater. The estimation methods and emission inventory will do help for the environmental management and emission reduction control of VOCs for potassium penicillin salt.