氧化型染发剂对沙蚕的毒性效应及对部分酶活性的影响

在实验室模拟条件下,研究了氧化型染发剂对双齿围沙蚕(Perinereis aibuhiteusis Grube)的急性毒性效应及不同暴露浓度(0、40、80、160、320mg·L-1)和暴露时间(0、4、6、8、10d)下对其体内乙酰胆碱酯酶(AChE)和超氧化物歧化酶(SOD)活性的影响.结果表明,1)暴露3d后氧化型染发剂对沙蚕的半数致死浓度(LC50)为1849.6mg·L-1;2)沙蚕体内AChE和SOD活性受到氧化型染发剂暴露浓度的显著影响:暴露3d后,随暴露浓度的升高(0～320mg·L-1),AChE和SOD活性均呈先被诱导后逐渐下降的变化趋势;3)沙蚕体内AChE和SOD活性也受到暴露时间的显著影响:40mg·L-1浓度下,随暴露时间的延长(0～10d),SOD活性呈先下降又缓慢上升的趋势,而AChE活性变化没有显著规律;4)通过比较发现,相对于AChE,SOD的活性变化更能反映氧化型染发剂对沙蚕的毒性作用.

Ecotoxic Effects of Oxidation Hair Dyes on Perinereis aibuhiteusis Grube and Its Enzyme Activities

Under the condition of laboratory simulation,the toxic effects of oxidation hair dyes on Perinereis aibuhiteusis Grube and its acetylcholinesterase(AChE)and superoxide dismutase(SOD)were examined. Results indicated that: 1) The value of LC50 was 1849.6mg·L-1 after a 3-day exposure to oxidation hair dyes. 2) The activities of AChE and SOD were influenced significantly by the exposure concentrations of oxidation hair dyes: After a 3-day exposure,the activities of AChE and SOD in exposure groups were higher than those of the control. With the increase of exposure concentrations(0~320mg·L-1),both AChE and SOD showed a tendency of inducement first and inhibition then. 3) The activities of AChE and SOD were influenced significantly by the exposure time(0~10d): The activity of SOD showed a tendency of inhibition first and inducement gradually then,however the activity of AChE changed irregularly. 4) Changes in the activity of SOD could reflect the toxic effect of oxidation hair dyes on Perinereis aibuhiteusis Grube better than that of AChE.