太湖梅梁湾水体和沉积物中有机污染物的遗传毒性

采用SOS/umu方法测试了太湖梅梁湾表层水和沉积物有机提取物的直接和间接遗传毒性,并与同期进行的化学分析数据进行了相关分析.结果表明,当暴露体积为40mL水样/孔时,绝大多数样点没有检出遗传毒性;而各样点的沉积物有机提取物表现出间接遗传毒性和显著剂量-效应关系.化学分析结果表明,梅梁湾沉积物中多环芳烃含量与间接遗传毒性之间存在相关性.因此,推测沉积物中存在间接致突变物质的积累,而多环芳烃可能是导致梅梁湾沉积物遗传毒性的主要风险因子之一.

Genotoxicity of organic pollutant water and sediment in Meiliang Bay, Taihu Lake

The direct and indirect genotoxicities of organic extracts from the surface waters and sediments of Meiliang Bay, Taihu Lake were assayed by the SOS/umu test. The bioassay results were compared with the simultaneously measured concentrations of polycyclic aromatic hydrocarbons (PAHs) in the sediments. There were no direct genotoxicities observed in sediment samples and there was only one water sample showing positive response in SOS/umu test under a dose level of 40mL per well. However, strong indirect genotoxicities were observed for all sediment samples, which showed to be significantly dose-dependent. In comparison with varies of chemical data, there was a significant correlation between levels of PAHs and potencies of indirect genotoxic effects. Therefore, there were accumulation of indirect mutagen and PAHs could be one of the major mutagenic stressors in the sediments of Meiliang Bay.