| 应用体外胃肠模拟法研究土壤中多氯联苯的生物有效性 |
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| 引用本文： | 徐瑾,陈广春,何欢,杨绍贵,孙成.应用体外胃肠模拟法研究土壤中多氯联苯的生物有效性[J].环境化学,2011,30(5):908-912. |
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| 作者姓名： | 徐瑾 陈广春 何欢 杨绍贵 孙成 |
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| 作者单位： | 南京大学环境学院,污染控制与资源化研究国家重点实验室,南京,210046 |
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| 基金项目： | 国家重点基础研究发展计划(2009CB421604)资助 |
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| 摘 要： | 采用体外胃肠模拟法,研究了土壤中多氯联苯的生物有效性.研究结果表明,PCBs在模拟胃液中的生物有效性为3.36%-12.48%,肠液中的生物有效性为34.62%-58.90%.胃肠液的pH值、消化时间及液固比均会影响其生物有效性:pH在中性时的生物有效性显著高于酸性条件下,消化时间的延长和液固比的增加均会使生物有效性增...
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| 关 键 词： | PCBs 体外实验 土壤 胃肠模拟 生物有效性 |
INVESTIGATION ON THE BIOACCESSIBILITY OF PCBS IN SOILS USING AN IN VITRO GASTROINTESTINAL MODEL |
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| XU Jin,CHEN Guangchun,HE Huan,YANG Shaogui,SUN Cheng.INVESTIGATION ON THE BIOACCESSIBILITY OF PCBS IN SOILS USING AN IN VITRO GASTROINTESTINAL MODEL[J].Environmental Chemistry,2011,30(5):908-912. |
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| Authors: | XU Jin CHEN Guangchun HE Huan YANG Shaogui SUN Cheng |
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| Institution: | XU Jin CHEN Guangchun HE Huan YANG Shaogui SUN Cheng(Sate Key Laboratory of Pollution Control and Resource Reuse,School of the Environment,Nanjing University,Nanjing,210046,China) |
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| Abstract: | A static in vitro gastrointestinal model was used to investigate the bioaccessibility of PCBs in soils.The results showed that the bioaccessibility of all PCB congeners ranged from 3.36% to 12.48% in the simulated gastric solution,and from 34.62% to 58.90% in the simulated intestinal solution.The main factors including pH values,digestion time and liquid/solid(L/S) ratios of the gastrointestinal solution were investigated.It was indicated that the bioaccessibility was enhanced with an increase in pH,digesti... |
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| Keywords: | PCBs in vitro soil gastrointestinal bioaccessibility |
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