Number of persistent organic pollutants detected at high concentrations in a general population |
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| Institution: | 1. CART, Organic and Biological Analytical Chemistry, Chemistry Department, University of Liège, Allée du 6 août, B6c, Sart-Tilman, B-4000 Liège, Belgium;2. CART, Mass Spectrometry Laboratory, Chemistry Department, University of Liège, Allée du 6 août, B6c, Sart-Tilman, B-4000 Liège, Belgium;3. INSERM U1085, Epidemiological Research on Environment, Reproduction and Development, Faculty of Medicine, University of Rennes, Campus de Beaulieu, 35042 Rennes, France;4. Ontario Ministry of the Environment, 125 Resources Road, Toronto, M9P 3V6 Ontario, Canada;1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;2. Institute of Environment and Health, Jianghan University, Wuhan 430056, China;3. Department of Geography and Environment, Baoji University of Arts and Sciences, Baoji 721013, China;4. MTM Research Center, School of Science and Technology, Örebro University, Örebro 70182, Sweden;1. Exposure and Biomonitoring Division, Health Canada, Ottawa, ON, Canada;2. Département de Pédiatrie, Faculté de Médecine, Université de Sherbrooke, Sherbrooke, Québec, Canada |
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| Abstract: | BackgroundSurveys of human exposure to environmental chemicals do not integrate the number of compounds detected per person and the concentration of each compound. This leaves untested relevant exposure scenarios, such as whether individuals with low concentrations of some compounds have high concentrations of the other compounds.ObjectiveTo analyze the number of persistent organic pollutants (POPs) detected at high concentrations.MethodsSerum concentrations of 19 POPs were analyzed by gas chromatography with electron-capture detection in a representative sample of the general population of Catalonia, Spain (N = 919).ResultsOver 58% of participants had concentrations in the top quartile of ≥ 1 of the eight most prevalent POPs, and 34% of ≥ 3 POPs. 83% of women 60 to 74 years old had concentrations of ≥ 3 POPs in the top quartile; 56% of women 60 to 74 years had p,p′-DDE, HCB and β-HCH all in their respective top quartiles, and 48% had concentrations of ≥ 6 POPs in the top quartile. Over 30% of subjects had concentrations in the top decile of 1 to 5 of the eight most prevalent POPs. Half of the population had levels of 1 to 5 POPs > 500 ng/g. Less than 4% had all eight POPs in the lowest quartile.ConclusionsMore than half of the study population had concentrations in the top quartile of ≥ 1 POPs. Significant subgroups of the population accumulate POP mixtures at high concentrations. POP concentrations appear low in most of the population only when each individual compound is looked at separately. |
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