| 谷胱甘肽S-转移酶的功能、应用及克隆表达 |
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| 引用本文： | 雷安平,陈欢,黎双飞,胡章立.谷胱甘肽S-转移酶的功能、应用及克隆表达[J].环境科学与技术,2009,32(12). |
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| 作者姓名： | 雷安平 陈欢 黎双飞 胡章立 |
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| 作者单位： | 深圳大学生态环境研究所,深圳大学生命科学学院,广东,深圳,518060 |
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| 基金项目： | 国家自然科学基金项目，国家自然科学基金项目，广东省自然科学基金项目 |
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| 摘 要： | 谷胱甘肽S-转移酶(glutathione S-transferases,GSTs,E.C.2.5.1.18)是由多个基因编码、具有多种功能的超家族酶,广泛存在于动物、植物、微生物等多种生物组织中。在生物体遇到高盐、干旱、除草剂、有机污染物等逆境时,GSTs常发挥其Ⅱ相代谢酶和抗氧化酶的双重功能,以保护生物体免受逆境的损害。文章综述了GSTs的分类、结构、功能、应用及克隆表达等方面的研究进展。
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| 关 键 词： | 谷胱甘肽S-转移酶(GSTs) 抗氧化 生物标记 克隆表达 |
Function,Application,Cloning and Expression of Glutathione Stransferases |
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| LEI An-ping,CHEN Huan,LI Shuang-fei,HU Zhang-li.Function,Application,Cloning and Expression of Glutathione Stransferases[J].Environmental Science and Technology,2009,32(12). |
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| Authors: | LEI An-ping CHEN Huan LI Shuang-fei HU Zhang-li |
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| Institution: | LEI An-ping,CHEN Huan,LI Shuang-fei,HU Zhang-li (Institute of Environmental Science & School of Life Science,Shenzhen University,Shenzhen 518060,China) |
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| Abstract: | This paper reviews current aspects in the study of glutathione S -transferases in terms of the classification, structure,application,function and cloning/expression. Glutathione S-transferases (GSTs,EC 2.5.1.18),encoded by multigenes,belong to a sort of super-family enzyme of multifunctional protein widely existing in animal,plants and microbes. GSTs could play a dual role in the cellular metabolism/detoxification which is characterized by the anti-oxidation against reactive oxygen species (ROS) caused by h... |
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| Keywords: | glutathione S-transferases (GSTs) antioxidation bio-marker |
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