Multi-component synthesis and antimicrobial activity of novel imidazo[4,5-f] indol-7-yl)indolin-2-ones |
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| Authors: | Malladi Srinivas Reddy Ramakrishna Saini Sudheer Kumar Dontamalla B Suhasini |
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| Institution: | 1. Department of Pharmaceutical Chemistry, Vaageswari College of Pharmacy, JNTU-Hyderabad, Thimmapur, Indiamsr.srinivas@gmail.com drmsreddy@vcpk.ac.in;3. Department of Chemistry, Kakatiya University, Warangal, India;4. Department of Pharmacy, K.D.R. Government Polytechnic, State Board of Technical Education and Training, Wanaparthy, India;5. Department of Pharmaceutical Chemistry, SVS School of Pharmacy, Warangal, India |
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| Abstract: | A three-component one-pot protocol has been investigated for the synthesis of imidazo4,5-f]indol-7-yl)indolin-2-ones from the commercially available materials. Structures of these compounds were established on the basis of IR, 1H NMR, and mass spectral data. The title compounds were evaluated for their antimicrobial activity. Two compounds exhibited the potent antimicrobial activity. |
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| Keywords: | imidazo[4 5-f]indol-7-yl)indolin-2-ones multi-component reaction ceric ammonium nitrate antimicrobial activity |
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