EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands;2. Department of Fetal Medicine and Prenatal Diagnosis, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands;3. Department of Obstetrics and Gynecology, Fetal Medicine Unit, Academic Medical Center, Amsterdam, the Netherlands;4. Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Research Institutes GROW and CAPHRI, Maastricht University, Maastricht, the Netherlands;5. Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands