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DDT, DDE, and 1-hydroxypyrene levels in children (in blood and urine samples) from Chiapas and Oaxaca, Mexico
Authors:Iván N Pérez-Maldonado  Antonio Trejo-Acevedo  Lucia Guadalupe Pruneda-Alvarez  Octavio Gaspar-Ramirez  Selene Ruvalcaba-Aranda  Francisco Javier Perez-Vazquez
Institution:1. Laboratorio de Toxicología Molecular, Centro de Investigación Aplicada en Ambiente y Salud (CIAAS), Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Avenida Sierra Leona No. 550, Colonia Lomas Segunda Sección, San Luis Potosí, 78210, SLP, México
2. Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Sierra Leona No. 550, Colonia Lomas Segunda Sección, San Luis Potosí, 78210, SLP, México
3. Unidad Académica Multidisciplinaria Zona Media, Universidad Autónoma de San Luis Potosí, Avenida Sierra Leona No. 550, Colonia Lomas Segunda Sección, San Luis Potosí, 78210, SLP, México
4. Centro Regional de Investigación en Salud Publica/Instituto Nacional de Salud Pública, Chiapas, Mexico
Abstract:The aim of this study was to evaluate the DDT, DDE, and 1-hydroxypyrene exposure levels of children living in communities located in southeastern Mexico. The study communities were Lacanja and Victoria in Chiapas state and Ventanilla in Oaxaca state. Children living in Lacanja had total blood DDT levels (mean?±?SD, 29,039.6?±?11,261.4 ng/g lipid) that were significantly higher than those of children in Victoria (10,220.5?±?7,893.1 ng/g lipid) and Ventanilla (11,659.7?±?6,683.7 ng/g lipid). With respect to the 1-hydroxypyrene levels in urine samples, the levels in Lacanja (4.8?±?4.1 μg/L or 4.5?±?3.9 μmol/mol creatinine) and Victoria (4.6?±?3.8 μg/L or 3.9?±?3.0 μmol/mol Cr) were significantly higher than levels found in Ventanilla (3.6?±?1.4 μg/L or 2.5?±?0.5 μmol/mol Cr). In conclusion, our data indicate high levels of exposure in children living in the communities studied in this work. The evidence found in this study could be further used as a trigger to revisit local policies on environmental exposures.
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