环境蛋白组学及污染物分子毒性检测技术

环境蛋白组学是蛋白组学与环境科学交叉融合的新兴学科,研究污染环境与蛋白组之间的相互作用规律与检测技术方法.环境蛋白组学的发展,取决于双向凝胶电泳、质谱、蛋白质芯片和生物信息学等技术的完善与应用.综述环境蛋白组学的主流技术,介绍环境蛋白组学技术在污染物分子毒性检测中的应用,探索污染物与蛋白组之间的相互作用机理,是人体与环境健康科技发展的起步过程.

Environmental Proteomics and Technology on Measurement of Pollutant Molecular Toxicity

Environmental proteomics is an inter-discipline between environmental sciences and proteomics. Its target is to research the principles and techniques for protein expression under polluted environment. The techniques of two-dimensional gel electrophoresis, mass spectrometry, protein chip and bioinformatics have promoted environmental proteomics rapidly. The summarization of environmental proteomics knowledge, main techniques for the examination of pollutant molecular toxicities, and interaction principle between pollutant and proteomic would be an outstanding milestone to protect human and environmental health.