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Horses and cows might teach us about human knees |
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| Authors: | C Holland F Vollrath H S Gill |
| Institution: | 1. Department of Zoology, University of Oxford, South Parks Road, Oxford, UK 2. Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield, UK 3. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford, UK 4. Department of Mechanical Engineering, University of Bath, Claverton Down, Bath, UK |
| Abstract: | Our comparative study of the knees of horses and cows (paraphrased as highly evolved joggers and as domesticated couch-potatoes, respectively) demonstrates significant differences in the posterior sections of bovine and equine tibial cartilage, which are consistent with specialisation for gait. These insights were possible using a novel analytical measuring technique based on the shearing of small biopsy samples, called dynamic shear analysis. We assert that this technique could provide a powerful new tool to precisely quantify the pathology of osteoarthritis for the medical field. |
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