50 Hz alternating extremely low frequency magnetic fields affect excitability,firing and action potential shape through interaction with ionic channels in snail neurones |
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Authors: | Mehri Kaviani Moghadam Saied Mohammad Firoozabadi Mahyar Janahmadi |
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Institution: | (1) Neuroscience Research Center and Department of Physiology, Medical Faculty, Shaheed Beheshti Medical Sciences University, Evin, P.O. Box 19835-181, Tehran, Iran;(2) Department of Medical Physics, Medical Faculty, Tarbiat Modarres University, Tehran, Iran |
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Abstract: | In spite of growing concern about the influence of magnetic fields on biological systems, the interaction between extremely
low frequency magnetic field (ELF magnetic fields) and biological structures at the cellular level remains obscure. The aim
of this study was to investigate if 50 Hz magnetic fields could have an effect on the neuronal excitability and firing responses.
Under Current-Clamp condition, exposure to 50 Hz ELF magnetic fields at 2 mT or 0.8 mT intensities resulted in an increase
in the peak amplitude of action potential and after hyperpolaization potential in a time dependent manner. Both magnetic field
intensities decreased also the firing frequency and the duration of action potential. Taken together, these data suggest that
50 Hz ELF magnetic fields at 2 mT or 0.8 mT intensities may change the electrophysiological behavior of neuronal cells and
underlying ion channel currents. |
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Keywords: | Magnetic fields Ion channels Helix aspersa Neuronal excitability |
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