Joint effects of Penta-BDE and heavy metals on Daphnia magna survival, its antioxidant enzyme activities and lipid peroxidation |
| |
Authors: | Baohua Tang Lingyan Zhu and Qixing Zhou |
| |
Institution: | (1) College of Biological and Environmental Engineering, Zhejiang University of Technology, 310032 Hangzhou, Zhejiang, China |
| |
Abstract: | The joint toxicity of Penta-BDE (Pe-BDE) and heavy metals including cadmium and copper on Daphnia magna (D. magna) was evaluated on the basis of determining the 48 h survival, antioxidative enzyme responses, and lipid peroxidation. The
response was classified as additive, greater than additive, or less than additive by comparing the measured “toxic units,
TU” with one. Based on the survival of D. magna, less-than-additive interactions were found in most of mixtures treatments. This may be attributed to the different toxicity
mechanism between Pe-BDE and metals. Cu and Cd played a greater role in toxicity than what Pe-BDE did. As for the superoxide
dismutase (SOD) and catalase (CAT) activity, most response was less than additive. For the glutathione S-transferases (GST) activity, most of the greater-thanadditive responses were found in the Cu plus Pe-BDE treatments, but
the additive responses occurred in Cd plus Pe-BDE treatments and binary metal treatments. For lipid peroxide levels, which
were measured as malondialdehyde (MDA) levels, less-than-additive response occurred in the 50% Cd plus 50% Cu and ternary
mixture treatments. Results suggested that Pe-BDE, Cd, and Cu could induce different patterns of antioxidant enzyme responses,
such as antioxidant/prooxidant responses, depending on their capability to produce reactive oxygen species and antioxidant
enzymes to detoxify them. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|