Interacting effects of pyrethroid and hormone on catalase and protein for toxicity amelioration in the freshwater fish, <Emphasis Type="Italic">Clarias batrachus</Emphasis>

Ameliorating effects of cortisol and T₃ on alphamethrin-dependent changes in the catalase (CAT) and protein profile of the freshwater catfish, Clarias batrachus, were studied. CAT activity and specific activity decreased in the liver, heart, kidney, and intestine after exposure to alphamethrin for 14 days. The administration of cortisol to alphamethrin-exposed fish brought the activity and specific activity of CAT up to their control values. The protein content decreased in different tissues of the fish after exposure to alphamethrin. The administration of T₃ to alphamethrin-exposed fish reduced the protein content to the control value. Therefore, it can be suggested that cortisol and T₃ may be used to ameliorate the toxicological effects of alphamethrin in fish.