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The impact of pesticides on oxidative stress level in human organism and their activity as an endocrine disruptor |
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| Authors: | Agata Jab?ońska-Trypu? El?bieta Wo?ejko Urszula Wydro Andrzej Butarewicz |
| Institution: | 1. Faculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Bia?ystok, Polanda.jablonska@pb.edu.pl;3. Faculty of Civil Engineering and Environmental Engineering, Department of Sanitary Biology and Biotechnology, Bialystok University of Technology, Bia?ystok, Poland |
| Abstract: | Pesticides cause serious environmental and health problems both to humans and animals. The aim of this review is to discuss selected herbicides and fungicides regarding their mode of action and their influence on basic oxidative stress parameters and endocrine disruption properties tested in selected cell cultures in vitro. Because of numerous difficulties which animal studies are subject to, cell cultures are an excellent experimental model reflecting human exposure to different pesticides through all relevant routes. This experimental model can be used to monitor aggregate and cumulative pesticide exposures. |
| Keywords: | Pesticides fungicides herbicides cell culture oxidative stress endocrine disruption |