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1-硝基芘和多环芳烃联合致突变性的研究
引用本文:竺乃恺,张朝,夏希娟,杜秀英.1-硝基芘和多环芳烃联合致突变性的研究[J].环境科学学报,2000,20(5):612-615.
作者姓名:竺乃恺  张朝  夏希娟  杜秀英
作者单位:中国科学院生态环境研究中心!北京100085
基金项目:国家自然科学基金!( 2 98371 80 ),中国科学院资助!(KZ 951 B/2 0 9 0 6)
摘    要:测定了1-硝基芘(1-NP)和其它(硝基一)多环芳烃对A试验的6个菌株(TA98,TA100,YG1021,YG1024,YG1026,YG1029)的单一和联合致突变性,1,6-二硝基芘(1.6DNP)、1-硝基芘(1-NP)和2-硝基坊(2-NF)所单一致突变性都为YG1024,YG1021,TA98,YG1026,YG1029,TA100,地2-NF的敏感性稍有差别,联合致突变性实验结果表明

关 键 词:硝基芘  多环芳烃  联合致突变性  污染物质
收稿时间:1999/7/22 0:00:00
修稿时间:1999-07-22

The Research on the joint mutagenicity of mixtures of 1-nitropyrene and nitro-PAHs
ZHU Naikai,ZHANG Zhao,XIA Xijuan and DU Xiuying.The Research on the joint mutagenicity of mixtures of 1-nitropyrene and nitro-PAHs[J].Acta Scientiae Circumstantiae,2000,20(5):612-615.
Authors:ZHU Naikai  ZHANG Zhao  XIA Xijuan and DU Xiuying
Institution:Reserach Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085,Reserach Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085,Reserach Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085 and Reserach Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085
Abstract:The mutagenicities of 1\|nitropyrene(1\|NP),2\|nitrofluorene(2\|NF),1,6\|dinitropyrene(1,6\|DNP),and five PAHs on Salmonella typhimurium TA98,TA100,YG1021,YG1024,YG1026,YG1029 were studied.The results showed that 1,6\|DNP is the most potent mutagen,next is 1\|NP and the last is 2\|NF;However,the mutagenicities of all PAHs tested are negative.The orders of sensitivity for six strains to both of 1\|NP and 1,6\|DNP is YG1024,YG1021,TA98,YG1026,YG1029,TA100,but it is not for 2\|NF.The results of the joint mutagenicity of the mixtures of 1\|NP and each of NO\-2\|PAHs showed that 2\|NF and 1,6\|DNP strengthened the mutagenicity of 1\|NP,but inhibited by every PAHs.
Keywords:NP  NO  2\|PAHs  ames test  joint mutagenicity  sensitivity
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