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| 一种改进的多学习教与学优化算法 | |
| 作者单位： | ;1.广东石油化工学院计算机与电子信息学院 |
| 摘 要： | 针对传统教与学算法在解决复杂多峰函数优化问题时,具有局部最优且搜索开发能力较差的缺点,提出了一种改进的多学习教与学优化算法,新算法为学员的每一维加入不同的教学因子,设计了基于学员均值比较的教师选择策略和向教师及学员学习的多学习策略。基于多个单峰和多峰函数的仿真结果表明,新算法跟传统的、改进的教与学算法相比,在稳定性、寻优精度和收敛速度方面更具优势。 |
| 关 键 词： | 教与学优化算法 多学习策略 逐维变化教学因子 教师选择 |
Diagnosis of lethal or prenatal-onset autosomal recessive disorders by parental exome sequencing |
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| Authors: | Karen L Stals Matthew Wakeling Júlia Baptista Richard Caswell Andrew Parrish Julia Rankin Carolyn Tysoe Garan Jones Adam C Gunning Hana Lango Allen Lisa Bradley Angela F Brady Helena Carley Jenny Carmichael Bruce Castle Deirdre Cilliers Helen Cox Charu Deshpande Abhijit Dixit Jacqueline Eason Frances Elmslie Andrew E Fry Alan Fryer Muriel Holder Tessa Homfray Emma Kivuva Victoria McKay Ruth Newbury-Ecob Michael Parker Ravi Savarirayan Claire Searle Nora Shannon Deborah Shears Sarah Smithson Ellen Thomas Peter D Turnpenny Vinod Varghese Pradeep Vasudevan Emma Wakeling Emma L Baple Sian Ellard |
| Institution: | 1. Molecular Genetics Department, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK;2. Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK;3. Molecular Genetics Department, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK
Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK;4. Clinical Genetics Department, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK;5. Department of Clinical Genetics, Our Lady's Children's Hospital, Dublin, Ireland;6. North West Thames Regional Genetics Service, London North West Healthcare NHS Trust, Harrow, UK;7. Guy's Regional Genetics Service, Guy's and St Thomas' NHS Foundation Trust, London, UK;8. Oxford Regional Clinical Genetics Service, Northampton General Hospital, Northampton, UK;9. Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK;10. West Midlands Medical Genetics Department, Birmingham Women's Hospital, Birmingham, UK;11. Department of Clinical Genetics, City Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK;12. South West Thames Regional Genetics Service, St George's University Hospitals NHS Foundation Trust, London, UK;13. Institute of Medical Genetics, University Hospital of Wales, Cardiff, UK;14. Department of Clinical Genetics, Liverpool Women's NHS Foundation Trust, Liverpool, UK;15. Department of Clinical Genetics, University Hospital Bristol, Bristol, UK;16. Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK;17. Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Vic, Australia;18. Leicester Clinical Genetics, Women's and Children's Services, Leicester Royal Infirmary, Leicester, UK;19. Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK Clinical Genetics Department, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK Wessex Clinical Genetics Service, University Hospital Southampton NHS Foundation Trust, Southampton, UK |
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