Transfer-RNA,an early gene? |
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Authors: | Manfred Eigen Ruthild Winkler-Oswatitsch |
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Institution: | 1. Max-Planck-Institut für biophysikalische Chemie, D-3400, G?ttingen
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Abstract: | The theory of self-reproductive molecular systems involves the consequence that translation must have started from a selected distribution of RNA molecules, that comprised GC-rich sequences of a length < 100 nucleotides. This implies a joint function of messenger and adaptor, which both had to be recruited from the same mutant distribution. The reconstruction of tRNA precursors yields such a molecule showing some reverberation of a codon pattern GNC. These findings suggest that tRNA has been the earliest component of the translation machinery. |
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