Polychlorinated biphenyls and selected organochlorine pesticides in serum of Slovak population from industrial and non-industrial areas |
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Authors: | Jana Chovancová Beáta Drobná Anna Fabi?iková Kamil ?onka Soňa Wimmerová Marian Pavuk |
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Institution: | 1. Department of Toxic Organic Pollutants, Slovak Medical University, Limbová 12, 833 03, Bratislava, Slovak Republic 2. Department of Biostatistical Analyses, Slovak Medical University, Limbová 12, 833 03, Bratislava, Slovak Republic 3. SpecPro Inc, 12500 San Pedro Avenue, San Antonio, TX, 78216, USA
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Abstract: | The concentrations of indicator polychlorinated biphenyls (PCBs No. 28, 52, 101, 138, 153 and 180) and organochlorine pesticides (HCB, p,p′-DDE and p,p′-DDT) in 121 blood serum specimens collected from non-occupationally exposed adults living in contaminated and comparison areas were determined using high-resolution gas chromatography/electron capture detection (HRGC/ECD). The sum of the serum concentrations of the three most abundant PCB congeners (No. 138, 153 and 180) found in participants (N?=?81) living in industrial areas near incinerators, metallurgical and chemical plants (Krompachy, Kosice, Nemecka and Sala) was significantly higher (p?0.001) than in participants living in villages and towns without known sources causing persistent organic pollutant (POP) contamination (N?=?40). Similarly, significant differences were observed for p,p′-DDE (p?0.0001) and p,p′-DDT (p?0.002). However, a Mann-Whitney U test between groups showed that the difference for HCB was not statistically significant (p?=?0.089). Age was positively correlated with the sum of PCBs (No. 138, 153 and 180), HCB and the sum of p,p′-DDE and p,p′-DDT (p?0.01 for all). |
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