Effect of lindane on antibody response to typhoid vaccine in weanling rats |
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| Authors: | A Dewan SK Gupta JP Jani SK Kashyap |
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| Institution: | National Institute of Occupational Health , Ahmedabad, 380016, Gujarat, India |
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| Abstract: | Abstract The immunosuppressive effect of lindane was assessed in weanling rats over a period of 5 weeks. Agglutinin titres against S. typhi ‘O’ and ‘H’, S. paratyphi ‘AH’ and ‘BR’ antigens were determined following TAB vaccination in control and lindane‐fed animals. The titres attained in non‐treated controls were higher significantly than those in treated animals indicating a suppressive effect of lindane on humoral immune responses. |
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| Keywords: | immunosuppressive effects r‐HCH titres |
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