Biomonitoring perfluorinated compounds in Catalonia,Spain: concentrations and trends in human liver and milk samples |
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Authors: | Kärrman Anna Domingo José L Llebaria Xavier Nadal Martí Bigas Esther van Bavel Bert Lindström Gunilla |
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Institution: | 1.Man-Technology-Environment Research Center (MTM), School of Science and Technology, ?rebro University, 701 82, ?rebro, Sweden ;2.Laboratory of Toxicology and Environmental Health, ‘Rovira i Virgili’ University, Sant Lloren? 21, 43201, Reus, Catalonia, Spain ;3.Health Protection Agency, Department of Health, Generalitat de Catalunya, Roc Boronat 81-95, 08005, Barcelona, Catalonia, Spain ; |
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Abstract: | Background, aim and scope Perfluorinated compounds (PFCs) are global environmental pollutants that bioaccumulate in wildlife and humans. Laboratory
experiments have revealed toxic effects such as delayed development, humoral suppression, and hepatotoxicity. Although numerous
human blood levels have been reported, little is known about distribution in the human body. Knowledge about PFC distribution
and accumulation in the human body is crucial to understanding uptake and subsequent effects as well as to conduct risk assessments.
The present study reports PFC levels in human liver and breast milk from a general population living in Catalonia, Spain.
Liver and milk levels are compared to previously reported levels in blood from the same geographic area as well as to other
existing reports on human liver and milk levels in other countries. |
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