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An Air Quality Data Analysis System for Interrelating Effects,Standards, and Needed Source Reductions: Part 11. A Lognormal Model Relating Human Lung Function Decrease to O3 Exposure
Authors:Ralph I Larsen  William F McDonnell  Donald H Horstman  Lawrence J Folinsbee
Institution:1. U.S. Environmental Protection Agency, Research Triangle Park , North Carolina , USA;2. ABB Environmental Services, Inc. , Chapel Hill , North Carolina , USA
Abstract:Forced expiratory volume in 1 second (FEV1) was measured in 21 men exercising while exposed to four O3 concentrations (0.0,0.08,0.10, and 0.12 ppm). A lognormal multiple linear regression model was fitted to their mean FEV1 measurements to predict FEV1 percent decrease as a function of O3 concentration and exposure duration. The exercise level used was probably comparable to heavy manual labor. The longest O3, exposure studied was 6 h. Extrapolating cautiously to an 8-h workday of heavy manual labor, the model predicts that O3 concentrations of 0.08, 0.10, and 0.12 ppm would decrease FEV1 by 9,15, and 20 percent, respectively.
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