兰州市大气中苯并(a)芘与儿童尿中1-羟基芘的分析及风险评价

对兰州市不同区域空气中苯并(a)芘和儿童尿液中1-羟基芘同步采样,分别采用气相色谱-质谱联用法和高效液相色谱法进行检测.结果表明:不同区域苯并(a)芘浓度有显著差别,研究区日均浓度约为对照区日均浓度的两倍.冬季大气中的浓度明显高于夏季,其中研究区冬季均值约为夏季的26.46倍,对照区冬季均值约为夏季的29.41倍.儿童尿中1-羟基芘的浓度与空气中苯并(a)芘的浓度呈一致的变化,冬季研究区儿童尿中1-羟基芘的均值为0.86μmol·(mol肌酐)-1,对照区为0.63μmol·(mol肌酐)-1.冬季研究区儿童的终生超额危险度最高,达到2.32×10-4,接近不可接受水平.

Analysis and risk assessment of air benzo(a)pyrene and children urinary 1-hydroxypyrene in Lanzhou City

The benzo(a)pyrene in the ambient air and the 1-hydroxypyrene in children’s urine were sampled in parallel from different areas in Lanzhou City.The samples were analysed respectively by gas chromatography-mass spectrometry and high performance liquid chromatography.The results showed that the concentrations of benzo(a)pyrene from different areas were significantly different,and the daily average concentration of benzo(a)pyrene in the study area was about two times that in the control area.The concentration of benzo(a)pyrene in winter was significantly higher than that in summer,and the average concentration in winter was 26.46 times and 29.41 times that in summer in the study area and control area,respectively.The variation of the concentration of 1-hydroxypyrene in children’s urine was correlated with the changes of benzo(a)pyrene in the ambient air.In winter,the mean value of urinary 1-hydroxypyrene was 0.86 μmol ·(mol creat)-1 in study area and 0.63 μmol ·(mol creat)-1 in control area.Children’s lifetime excess risk in the study area was the highest,which reached the level of 2.32×10-4 and was close to the unacceptable level according to the U.S.EPA criteria.