东莞市蔬菜基地蔬菜中喹诺酮类抗生素污染特征及健康风险

利用超高效液相色谱-串联质谱(UPLC-MS/MS)技术分析了东莞市蔬菜基地蔬菜中4种喹诺酮类抗生素的污染特征,并对其健康风险进行评价.结果表明,东莞市蔬菜中普遍检出喹诺酮类抗生素,以诺氟沙星和环丙沙星为主,其次是恩诺沙星,检出率均在80%以上,最高含量均大于100μg/kg(干重),平均含量近20μg/kg;不同基地和不同类型的蔬菜中喹诺酮类抗生素的含量与组成特征差异较大,总含量为叶菜类(49.87μg/kg)>根茎类(44.81μg/kg)>瓜果类(11.21μg/kg);通过食用东莞市蔬菜摄入喹诺酮类抗生素的量低于日允许摄入量,健康风险较小.

Content levels and health risk of quinolone antibiotics from vegetables of Dongguan farms

Quinolone antibiotics in vegetables from Dongguan vegetable farms were determined using ultra high performance liquid chromatography-tandem mass spectrometry and the health risk of their exposure to human body by diet pathway was assessed. The results showed that quinolone antibiotics in the vegetable samples were frequently detected. Norfloxacin and ciprofloxacin were main compounds,followed by enrofolxacin, and the three antibiotics were detected in more than 80% of the samples.The highest content of individual compounds was more than 100μg/kg (D.W.) and average contents was around 20μg/kg (D.W.). The composition and concentration of quinolone antibiotics in various farms of vegetables and different kinds of vegetables varied greatly, with the order of leafy vegetable (49.87μg/kg) >rhizome vegetable (44.81μg/kg)> melon-fruit vegetable (11.21μg/kg). The intake dose of quinolone antibiotics via the consumption of vegetable from Dongguan farms was lower than acceptable daily intake (ADI), suggesting a lower health risk.