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| 亚氯酸盐对三代大鼠的胚胎毒性 | |
| 引用本文： | 吴明松,李绍峰,李百祥,张玉玲,黄君礼,田禹.亚氯酸盐对三代大鼠的胚胎毒性[J].中国环境科学,2011,31(11):1900-1903. |
| 作者姓名： | 吴明松 李绍峰 李百祥 张玉玲 黄君礼 田禹 |
| 作者单位： | 1. 哈尔滨工业大学,城市水资源与水环境国家重点实验室,黑龙江哈尔滨150090 2. 深圳职业技术学院建筑与环境工程学院,广东深圳,518055 3. 哈尔滨医科大学公共卫生学院,黑龙江哈尔滨,150006 |
| 摘 要： | 通过三代染毒实验,研究了亚氯酸盐对Wistar大鼠的长期胚胎毒性.结果表明:亚氯酸盐对胎鼠的内脏、骨骼发育无影响,没有表现出致畸作用,但长期摄入120,360mg/L亚氯酸盐可导致胎鼠体重减轻.亚氯酸盐对胎鼠的无明显副作用剂量为30mg/L,由实验结果可推算饮用水中亚氯酸盐最大污染水平目标值推算为1.1mg/L. |
| 关 键 词： | 二氧化氯 消毒 亚氯酸盐 毒性 |
| 收稿时间： | 2011-02-04; |
Embryo toxicity of sodium chlorite on three generation rats |
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| WU Ming-song,LI Shao-feng,LI Bai-xiang,ZHANG Yu-ling,HUANG Jun-li,TIAN Yu.Embryo toxicity of sodium chlorite on three generation rats[J].China Environmental Science,2011,31(11):1900-1903. | |
| Authors: | WU Ming-song LI Shao-feng LI Bai-xiang ZHANG Yu-ling HUANG Jun-li TIAN Yu |
| Institution: | WU Ming-song1,LI Shao-feng2,LI Bai-xiang3,ZHANG Yu-ling1,HUANG Jun-li1,TIAN Yu1(1.Key Laboratory of Water Resource Utilization and Environmental Pollution Control,Harbin Institute of Technology,Harbin 150090,China,2.Department of Architecture Engineering,Shenzhen Polytechnic Institute,Shenzhen 518055,3.The Public Health School,Harbin Medical University,Harbin 150006,China) |
| Abstract: | The embryo toxicity of chlorite on Wistar rat was investigated through a three-generation test.No teratogenic effect,abnormal viscera and skeleton was observed on fetal rats.Exposure to 120 and 360mg/L chlorite for long term led to decreased body weights for the pups.No observed adverse effect level of chlorite on fetal rat was determined at 30mg/L,and the maximum contaminant level goal of chlorite in drinking water could be deduced as 1.1mg/L. |
| Keywords: | chlorine dioxide disinfection chlorite toxicity |
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