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| 动物性食品中PCBs的生物有效性及人体日暴露评估 | |
| 引用本文： | 李俊岭,张东平,余应新,韩姝媛,吴明红,盛国英,傅家谟.动物性食品中PCBs的生物有效性及人体日暴露评估[J].中国环境科学,2011,31(6):1019-1028. |
| 作者姓名： | 李俊岭 张东平 余应新 韩姝媛 吴明红 盛国英 傅家谟 |
| 作者单位： | 1. 上海大学环境与化学工程学院,环境污染与健康研究所,上海,200444 2. 上海大学环境与化学工程学院,上海射线应用研究所,上海,200444 3. 上海大学环境与化学工程学院,环境污染与健康研究所,上海,200444;中国科学院广州地球化学研究所,有机地球化学国家重点实验室,广东广州,510640 |
| 基金项目： | 国家自然科学基金资助项目，国家"973"项目，上海市重点学科项目 |
| 摘 要： | 通过测定上海市售动物性食品中PCBs的浓度和生物有效性,评估该地区PCBs的人体日暴露量.结果表明,不同种类食品中PCBs的浓度在未检出~3734.3pg/g(湿重)之间,3~6氯PCBs为主要同系物.鱼类中PCBs浓度高于畜类、禽类和软体类.鱼类PCBs的浓度水平遵循以下两规律:海水鱼>淡水鱼;肉食性鱼>杂食性鱼>草食性鱼.采用模拟人体胃肠消化过程测得PCBs的生物有效性,由于食品中脂肪含量与PCBs的生物有效性具有显著的线性关系,故可用于计算样品中PCBs的生物有效性.该地区居民每天通过动物性食品摄入的PCBs量为24439.3pg/d,以PCBs的生物有效性计量为5034.5pg/d.对不同暴露源(包括灰尘和大气颗粒物)的分析表明,鱼类是PCBs人体暴露的主要贡献者,约占人体PCBs日暴露的60%. |
| 关 键 词： | 多氯联苯 动物性食品 模拟胃肠道 生物有效性 日暴露 |
| 收稿时间： | 2010-10-09; |
Concentrations and bioaccessibility of polychlorinated biphenyls in animal-based food collected from markets in Shanghai and assessment of associated human daily intake |
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| LI Jun-ling,ZHANG Dong-ping,YU Ying-xin,HAN Shu-yuan,WU Ming-hong,SHENG Guo-ying,FU Jia-mo.Concentrations and bioaccessibility of polychlorinated biphenyls in animal-based food collected from markets in Shanghai and assessment of associated human daily intake[J].China Environmental Science,2011,31(6):1019-1028. | |
| Authors: | LI Jun-ling ZHANG Dong-ping YU Ying-xin HAN Shu-yuan WU Ming-hong SHENG Guo-ying FU Jia-mo |
| Institution: | LI Jun-ling1,ZHANG Dong-ping1,YU Ying-xin1,HAN Shu-yuan1,WU Ming-hong3,SHENG Guo-ying1,2,FU Jia-mo1,2(1.Institute of Environmental Pollution and Health,School of Environmental and Chemical Engineering,Shanghai University,Shanghai 200444,China,2.State Key Laboratory of Organic Geochemistry,Guangzhou Institute of Geochemistry,Chinese Academy of Sciences,Guangzhou 510640,3.Shanghai Applied Radiation Institute,China) |
| Abstract: | The concentrations and bioaccessibility of PCBs in animal-based food collected from markets in Shanghai were determined.The associated human daily intake of PCBs was estimated.The concentrations of PCBs ranged from lower than limit of detection to 3734.3 pg/g(wet weight).Tri-to hexa-CBs were the predominant congeners.The PCB concentrations in fish were higher than those in livestock,poultry or shellfish.The following sequences of PCB concentrations in fish were observed: seawater fish > freshwater fish;carn... |
| Keywords: | polychlorinated biphenyls animal food simulating human gastrointestinal tract bioaccessibility daily intake |
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