铁磁性纳米材料的制备及对17β-雌二醇的选择性富集——基于分子印迹技术

将铁磁性分离与分子印迹技术结合, 以四氧化三铁纳米颗粒为核, 以17β-雌二醇(E2)为模板分子, 3-氨基丙基三乙氧基硅烷(APTES)为功能单体, 利用表面聚合法制备了E2分子印迹纳米材料(MIPs)和不含E2的非印迹纳米材料(NIPs).通过傅里叶变换红外光谱(FT-IR)、X射线衍射(XRD)、X射线光电子能谱(XPS)和扫描电镜(SEM)等方法对MIPs和NIPs进行分析和表征, 显示MIPs形状规则呈球状粒径统一在790nm左右.选择吸附实验中, MIPs和NIPs对E2的饱和吸附量分别为9.69, 6.25mg/g, 说明材料具有较好的选择性.对静态吸附数据进行Freundlich线性拟合, 结果证明MIPs具有良好的吸附能力.同时, MIPs表现出优秀的可重复利用性, 7次吸附-解吸后吸附损失量仅为3%.

Preparation of ferromagnetic nanomaterials based on molecular imprinting technology and their performance for selective enrichment of 17β-estradiol (E2)

Ferromagnetic separation and molecular imprinting technology were combined together. Ferromagnetic oxide nanoparticles were used as core, while 17β-estradiol (E2) was used as the template molecule and (3-Aminopropyl) triethoxysilane was used as the functional monomer E2 molecularly imprinted polymer (MIPs) and non-imprinted polymer (NIPs) were prepared by surface polymerization. Then E2MIPs and NIPs were characterized by FT-IR, XRD, XPS, SEM and other methods. The results showed that MIPs have a regular spherical shape, and the particle size is uniform at about 790nm. In the selective adsorption experiment, the saturated adsorption capacity of MIPs and NIPs for E2 is 9.69 and 6.25mg/g, respectively. These results indicated good selectivity of the material. Freundlich linear fitting was performed on the static adsorption data, and the results proved that MIPs have good adsorption capacity. Meanwhile, MIPs showed excellent reusability as the adsorption capacity only lost 3% after 7 adsorption-desorption processes.