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用细胞电泳率指标检测膜毒性物质的探讨
引用本文:张贵利,戴修道,周德灏.用细胞电泳率指标检测膜毒性物质的探讨[J].上海环境科学,1998,17(3):42-44.
作者姓名:张贵利  戴修道  周德灏
作者单位:上海医科大学 上海200032 (张贵利,戴修道),上海医科大学 上海200032(周德灏)
摘    要:细胞电泳地是近期发展起来的一种检测细胞膜表面微小改变的生物学方法,当膜表面电荷密度分布受影响时,细胞在等强度电场作用下的移动速率会发生改变,根据电泳速率的改变,可以判断外源性物质对细胞膜是否具损伤作用。

关 键 词:环境污染物  细胞膜  毒性物质  电泳率  检测指标
修稿时间:1997年7月28日

Approach on Cell Membrane Toxicity Materials by Using Electrophoresis Ratio
Zhang guili,Dai Xiudao,Zhou Dehao.Approach on Cell Membrane Toxicity Materials by Using Electrophoresis Ratio[J].Shanghai Environmental Science,1998,17(3):42-44.
Authors:Zhang guili  Dai Xiudao  Zhou Dehao
Abstract:Cell electrophoresis is one of the biological methods developed recently for detecting the infinitesmall changes in cell membrane. When changes of charge distribution in membrance surfae, cell mobility ratio will change in the equal intensity electric field. Therefore, on the basis of the change of electrophoresis ratio, it can be decided whether a xenogenous chemical has the damage effect on cell membrane. The result of repeated experiments of cell electrophoresis showed that it might be an effective index to appreciate the membrane toxicity materials in the environment. The great advantages of this technique include sensitivity, high specificity, good duplicity, simple and rapid operation.
Keywords:Environment pollution Cell membrane Toxicity materials Cell electrophoresis Electrophoresis ratio Detection index
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