| HPLC-MS/MS法同时测定近岸底栖生物中15种磺胺类抗生素残留量 |
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| 引用本文： | 那广水,周传光,王 震,王 强,李红霞,陈 彤,张月梅,姚子伟.HPLC-MS/MS法同时测定近岸底栖生物中15种磺胺类抗生素残留量[J].环境科学研究,2009,22(4):434-437. |
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| 作者姓名： | 那广水 周传光 王 震 王 强 李红霞 陈 彤 张月梅 姚子伟 |
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| 作者单位： | 1.国家海洋环境监测中心,辽宁 大连 116023 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 采用液-液萃取和固相萃取方法处理生物样品，建立以ESI(+)和SRM为基础的快速检测15种磺胺的HPLC-MS/MS方法，并采用该方法对大连周边海域底栖生物中磺胺的残留状况进行了分析. 结果表明:近岸底栖生物中磺胺噻唑(STZ)、磺胺喹啉(SQX)、磺胺嘧啶(SDZ)和磺胺甲基异唑(SMZ)等检出率较高，质量分数为1.39～143.29 ng/g.说明在我国近岸底栖生物中已经有一定量的磺胺类抗生素的残留，并威胁到水生生物的安全，因此应加强对近岸海洋环境中抗生素残留的监测与管理.
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| 关 键 词： | 底栖生物 磺胺 液相色谱-串联质谱 抗生素残留 |
| 收稿时间： | 2008/7/25 0:00:00 |
| 修稿时间： | 2008/10/20 0:00:00 |
Simultaneous Determination of Fifteen Sulfonamide Residues in Macrobenthos by High-Performance Liquid Chromatography Tandem Mass Spectrometry |
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| NA Guang-shui,ZHOU Chuan-guang,WANG Zhen,WANG Qiang,LI Hong-xi,CHEN Tong,ZHANG Yue-mei and YAO Zi-wei.Simultaneous Determination of Fifteen Sulfonamide Residues in Macrobenthos by High-Performance Liquid Chromatography Tandem Mass Spectrometry[J].Research of Environmental Sciences,2009,22(4):434-437. |
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| Authors: | NA Guang-shui ZHOU Chuan-guang WANG Zhen WANG Qiang LI Hong-xi CHEN Tong ZHANG Yue-mei and YAO Zi-wei |
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| Institution: | 1.National Marine Environmental Monitoring Center, Dalian 116023, China2.College of Life Science and Technology, Dalian Fisheries University, Dalian 116023, China3.College of Biological & Food Technology, Dalian Polytechnic University, Dalian 116034, China |
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| Abstract: | This study used a rapid method for the determination of 15 kinds of sulfonamides(SAs) in macrobenthos using LLE-SPE,and LC-MS/MS with positive ESI(ESI(+)) and selected reaction monitoring(SRM) mode.The method was applied to quantify the SAs residue in macrobenthos around Dalian.The results showed that sulfathiazole(STZ),sulfathiazole(SQX),sulfadiazine(SDZ) and sulfamethoxazole(SMZ) were frequently found in macrobenthos in a concentration range between 1.39 and 143.29 ng/g.This indicated that there was antib... |
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| Keywords: | macrobenthos sulfonamides HPLC-MS/MS antibiotics residue |
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