| 不同金属离子对Vc引发的小鼠肝匀浆自由基反应的影响 |
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| 引用本文： | 李海蓉,侯少范,王五一.不同金属离子对Vc引发的小鼠肝匀浆自由基反应的影响[J].环境科学,2003,24(2):139-142. |
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| 作者姓名： | 李海蓉 侯少范 王五一 |
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| 作者单位： | 中国科学院地理科学与资源研究所,北京,100101 |
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| 摘 要： | 以小鼠肝匀浆脂质过氧化产物丙二醛(MDA)的OD532nm值(MDA-OD532nm)作为测定自由基反应的间接指标,研究了Hg2+、Mn2+、Ni2+、Cd2+、Cr3+、SeO2-3等离子和As2O3水溶液在Vc引发自由基反应体系中的作用.结果表明:Cr3+与Mn2+具有显著的抑制作用;Hg2+、Cd2+与As2O3对自由基反应有促进作用;Ni2+、SeO2-3对Vc引发小鼠肝匀浆的自由基反应作用不明显.
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| 关 键 词： | Vc 自由基反应 MDA-OD532nm值 金属离子 |
| 文章编号： | 0250-3301(2003)02-04-0139 |
| 收稿时间： | 2002/5/10 0:00:00 |
| 修稿时间： | 2002年5月10日 |
The Action of Different Kinds of Ions on Free Radical Reaction Induced by Vc in Rat Liver Homogenate |
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| Li Hairong,Hou Shaofan and Wang Wuyi.The Action of Different Kinds of Ions on Free Radical Reaction Induced by Vc in Rat Liver Homogenate[J].Chinese Journal of Environmental Science,2003,24(2):139-142. |
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| Authors: | Li Hairong Hou Shaofan and Wang Wuyi |
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| Institution: | Institute of Geographic Sciences and Natural Resource Research, Chinese Academy of Sciences, Beijing 100101, China. |
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| Abstract: | The value of OD532 nm of malondialdehyed(MDA) formed by lipid peroxidation was used as an indirect index of reaction of free radicals. The roles of Hg2+, Mn2+, Ni2+, Cd2+, Cr3+, SeO3(2-) and water solution of As2O3 in vitro system of ascorbic acid producing free radicals were studied. The results indicated that Mn2+ and Cr3+ inhibited free radicals induced by ascorbic acid but on the contrary, Hg2+, Cd2+ and As2O3 showed an enhancing effect, and the roles of Ni2+, SeO3(2-) were ambiguous. |
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| Keywords: | Vc free radicals reaction MDA OD 532nm metallic ions |
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