养殖鳜鱼体内典型有机氯化合物的检测与人体健康风险评估初探

利用GC-ECD检测了江苏省吴江市某养殖塘内的一批鳜鱼体内有机氯农药（OCPs）和多氯联苯（PCBs）等典型有机氯化合物（OCs）的含量水平,并对其人体健康风险进行了初步评估.结果表明,养殖鳜鱼体内滴滴涕（DDTs）、六六六（HCHs）、六氯苯（HCB）和PCBs的含量范围分别为1.3～4.57、0.13～1.24、0...

Measurement and Preliminary Human Health Risk Assessment of Representative Organochlorines in Farmed Mandarin Fish

Concentrations of representative organochlorines (OCs), including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in a batch of farmed mandarin fish from a cultivation pond in Wujiang City, Jiangsu Province, were determined with GC-ECD. Meanwhile, a preliminary human health risk assessment was conducted. Results showed that, the concentrations of dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB) and PCBs in the farmed mandarin fish were in the range of 1.3-4.57 ng/g, 0.13-1.24 ng/g, 0.07-0.44 ng/g and 0-5.22 ng/g, respectively, with an average value of 2.96, 0.40, 1.27 and 0.7 ng/g, respectively. These values were far below the corresponding residue limits set by China's Ministry of Health and the U.S. Food and Drug Administration, and at the low end of the global pollution bar. Referring to the reference values given by USEPA Integrated Risk Information System, calculated non-carcinogenic hazard ratios (HRs) of DDTs, HCB and PCBs were all <1 and carcinogenic HRs of DDTs, HCHs, HCB and PCBs were all >1.The results indicated that DDTs, HCHs and HCB in farmed mandarin fish did not have negative human health influence, but existed potential carcinogenic risk to humans. Compared to rural residents, urban residents were more vulnerable to DDTs, HCHs, HCB and PCBs threats.