Prenatal diagnosis of a de novo unbalanced translocation (4p + ) following in vitro fertilization |
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| Authors: | Dr Linda A Cannizzaro Barbara K Hecht Helen A Bixenman Stephen Pazdziorko Robert Tamis Frederick Hecht |
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| Institution: | 1. The Genetics Center, Southwest Biomedical Research Institute of Genetics and Cancer, 6401 E. Thomas Road, Scottsdale, AZ 85251, U.S.A.;2. Arizona Fertility Institute, 2720 N. 20th Street, Phoenix AZ 85006, U.S.A. |
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| Abstract: | We report herein a de novo unbalanced chromosome translocation in a fetus resulting from in vitro fertilization technology. Prenatal diagnostic analysis of an amniotic fluid revealed a 46,XX,4p+ karyotype. The origin of the extra material on the short arm of chromosome 4 could not be identified by a variety of banding techniques. However, examination of fetal parts did reveal some dysmorphic features. |
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| Keywords: | 4p+ Translocation in vitro fertilization |
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