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ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome
Authors:Michael Christiansen  Kevin Spencer  Jennie Laigaard  Nicholas J Cowans  Severin Olesen Larsen  Ulla M Wewer
Institution:1. Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark;2. Prenatal Screening Unit, Clinical Biochemistry Department, Harold Wood Hospital, Romford, UK;3. Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark

Institute of Molecular Pathology, University of Copenhagen, Denmark;4. Institute of Molecular Pathology, University of Copenhagen, Denmark

Abstract:
Keywords:prenatal screening  PAPP-A  free β-hCG  growth factors  integrins  ADAM12  aneuploidy  trisomy 21
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