| 水库水氯化消毒副产物毒性研究 |
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| 引用本文： | 范丽莎,李玄,于衍真.水库水氯化消毒副产物毒性研究[J].环境保护科学,2014(5):24-27. |
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| 作者姓名： | 范丽莎 李玄 于衍真 |
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| 作者单位： | 1. 济南大学土木建筑学院,山东 济南,250022
2. 同济大学环境科学与工程学院,上海,200092 |
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| 摘 要： | 为了证实水库出水的氯化消毒副产物CHClBr2和CHBr3具有一定的遗传毒性,将水库出水进行浓缩富集研究其对小鼠脾脏淋巴细胞DNA的影响。同时分别与水库枯水期和丰水期出水的小鼠彗星实验结果进行了对比,发现氯化消毒副产物CHClBr2和CHBr3的DNA损伤效应同时高于两个水期的出厂水。
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| 关 键 词： | 消毒副产物 彗星实验 淋巴细胞 DNA损伤 氯化消毒 |
Genotoxicity Study of the By-products Generated from Reservoir Water Chlorination |
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| Fan Lisha,Li Xuan,Yu Yanzhen.Genotoxicity Study of the By-products Generated from Reservoir Water Chlorination[J].Environmental Protection Science,2014(5):24-27. |
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| Authors: | Fan Lisha Li Xuan Yu Yanzhen |
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| Institution: | Fan Lisha, Li Xuan, Yu Yanzhen (1.School of Civil Engineering and Architecture, University of Jinan, Jinan 250022, China; 2.College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China) |
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| Abstract: | In this paper, to confirm that CHCIBr2 and CHBr＋ which are the by-products of chlorination in the reservoir effluent have a certain genetic toxicity, the concerned reservoir effluent is concentrated and enriched to study the effects of the byproducts on DNA damage of spleen lymphocytes in mice. Simultaneously, the results are compared with those of the mice comet assays of the reservoir water in low and high water periods respectively. It is found that the effects of CHClBr2 and CHBr＋ on DNA damage are higher than those of the reservoir water in both low and high water periods. |
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| Keywords: | CDBPs Comet Assay Lymphocyte DNA Damage Chlorination |
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