溴氰菊酯暴露与消化系统恶性肿瘤死亡率的相关性研究

分析环境中溴氰菊酯暴露与人群消化系统恶性肿瘤死亡率是否存在相关关系。方法收集1996~1999年沈阳市6个郊区县的溴氰菊酯暴露资料和1997~2002年消化系统恶性肿瘤死亡率资料,用SPSS(11.5)统计软件对每年农药使用密度与随后3年的消化系统恶性肿瘤平均死亡率进行Spearman等级相关分析。结果:每年的溴氰菊酯使用密度与随后3年的男性食管癌、胃癌、肝癌平均死亡率均显著相关。1997~1999年度溴氰菊酯使用密度与男性结直肠肛门癌死亡率有显著相关,而在1996年度不相关。在女性则相关的年份很少。结论:溴氰菊酯的暴露可能是男性食管癌、胃癌、肝癌死亡的危险因素之一。而其它相关结果尚不具有普遍性意义,今后仍需进一步深入开展相关方面的流行病学和毒理学研究。

Relative Study on Deltamelthrin Exposure and Mortality Due to Digestive System Sarcomata

To analyse the relationship between deltamelthrin exposure and mortality due to digestive system sarcomata,collect data of deltamelthrin exposure in 6 suburb counties of Shenyang in 1996～1999 and data of mortality due to digestive system sarcomata in 1997～2002,and analyse Spearman grade relativity of annual using pesticide density and average mortality due to digestive system sarcomata in following 3 years by SPSS(115) the relationship between annual using pesticide density and average mortality due to male Carcinomaofe Sophagus,Gastric Cancer and Hepatocellular carcinoma was remarkable.Significant correlations were found between annual using pesticide density and average mortality due to male carcinomaofrectum in 1997～1999,while no significant correlation was found in 1996.There were few years about that of female.Deltamelthrin exposure was one of the dangerous factors,which may lead to death owing to male carcinomaofe sophagus,Gastric Cancer and Hepatocellular carcinoma.Other results were not significant and studies should be taken deeply on epidemic and toxicology in the future.