聚丙烯酰胺生物降解研究进展

聚丙烯酰胺（PAM）是丙烯酰胺均聚物和各种共聚物的统称，作为一种高技术含量、高附加值的重要化工产品，已广泛应用到工农业生产的各个领域并渗透到人们的日常生活中．过去通常认为聚丙烯酰胺是非常稳定的高分子聚合物，事实上，在自然条件下，聚丙烯酰胺会发生缓慢的物理降解（热、剪切）、化学降解（水解、氧化以及催化氧化）和生物降解，最终生成各种低聚物以及具有神经毒性的剧毒丙烯酰胺单体，对人体造成了极大的间接或直接危害．因此，进行聚丙烯酰胺的降解研究很有意义，而聚丙烯酰胺的生物降解研究领域几乎为空白．参33

PROGRESS OF STUDIES ON POLYACRYLAMIDE BIODEGRADATION

Polyacrylamide (PAM) is a general term for acrylamide homopolymers and copolymers. As an important product of chemical industry with high-tech and high accessional values, polyacrylamide has been widely applied to different fields of industry and agriculture, and even to people's daily life. It was generally considered that polyacrylamide was an extraordinarily stable macromolecular polymer. But unfortunately, polyacrylamide is found with slow physical degradation (heat, cutting), slow chemical degradation (hydrolysis, oxidation, catalysis oxidation) and slow biodegradation under natural conditions, and it finally produced different oligomers, as well as acrylamide, which possess neurotoxicity, and are directly and indirectly harmful to human health. So, the studies on degradation of polyacrylamide are greatly inportant. However, there have been very few studies on biodegradation of polyacrylamide till now. Ref 33