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Correlation between lead and iron in children's blood in Jordan
Authors:Adnan M Massadeh  Wail A Hayajneh  Abdullah Shorman  Mohammad Y Gharaibeh  Moh'd Mohanad A Al-Dabet
Institution:1. Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordanmassadeh@just.edu.jo;3. Department of Pediatrics, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan;4. Princess Rahma Children Teaching Hospital, Irbid, Jordan;5. Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid Jordan
Abstract:A total of 200 Jordanian children were classified into two groups: 100 Fe replete and 100 Fe deficient with ages ranging between 3.0 and 12.0 years (6.9 ± 2.7 years). All participants were chosen according to proper selection criteria followed by the sample collection: the samples were analyzed for hemoglobin and red blood cells; ferritin, an immunoassays-based instrument; and levels of Pb, Cu, and Zn. There were no significant differences between genders regarding Fe-deficiency (p = 0.57 and χ2 = 0.33), with a significant association of younger individuals (3.0–9.1 years) with Fe-deficiency (p < 0.05 and χ2 = 22.7).

In addition, there is a significant positive correlation between Fe-deficiency with blood levels of Pb, Cu, and Zn (p < 0.05), (r = 0.43, 0.35, and 0.42, respectively) as compared to control group, this findings supported, by comparing the levels of the examined metals in both groups, in individuals whom close to heavy metals source (highway traffic or oil gas station), and found that the mean of the heavy metals level in close Fe-deficient group higher than in close Fe-replete group.
Keywords:lead  iron-deficient  iron-replete  copper  zinc  children blood
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