首页 | 本学科首页   官方微博 | 高级检索  
     检索      

中心复合设计射线法考察离子液体C16H31ClN2与乐果的毒性相互作用
引用本文:张晶,王金承,刘树深,葛会林,刘海玲.中心复合设计射线法考察离子液体C16H31ClN2与乐果的毒性相互作用[J].生态毒理学报,2009,4(3):353-358.
作者姓名:张晶  王金承  刘树深  葛会林  刘海玲
作者单位:1. 桂林工学院材料与化学工程系,桂林,541004
2. 同济大学环境科学与工程学院,长江水环境教育部重点实验室,上海,200092
基金项目:国家自然科学基金项目(No. 20777056);国家863计划专题课题(No. 2007AA06Z417)
摘    要:离子液体(ILs)是一种用于替代传统易挥发有机溶剂的新型"绿色"溶剂.由于不挥发、不会对大气产生污染而得到广泛应用.但是某些ILs易溶于水,其自身毒性能够对生态环境造成潜在影响,这已引起诸多学者对ILs毒性的研究兴趣.然而ILs与其它污染物的毒性相互作用目前研究很少.论文选取咪唑类离子液体C16H31ClN(2DMI)与有机磷杀虫剂乐果(DIM)作为目标化合物,以青海弧菌Q67为检测生物,采用微板毒性分析法测定了目标化合物及其混合物的毒性.为全面考察不同浓度范围DMI与DIM的毒性相互作用,将中心复合设计与固定浓度比射线法有机结合起来构建5个不同浓度比的混合物射线,通过浓度加和与独立作用模型对混合物射线进行比较评估.结果表明在DMI浓度较大且DIM浓度较低时,DMI与DIM之间存在明显拮抗作用,而在其它浓度范围内两者之间为加和作用.

关 键 词:C16H31ClN2  乐果  毒性相互作用  微板毒性分析  中心复合设计射线法
收稿时间:4/9/2009 12:00:00 AM
修稿时间:5/6/2009 12:00:00 AM

Study on the Toxicity Interaction between Dimethoate and C16 H31 ClN2 by Central Composite Design with the Fixed Concentration Ratio Ray
ZHANG Jing,WANG Jin-cheng,LIU Shu-shen,GE Hui-lin,LIU Hai-ling.Study on the Toxicity Interaction between Dimethoate and C16 H31 ClN2 by Central Composite Design with the Fixed Concentration Ratio Ray[J].Asian Journal of Ecotoxicology,2009,4(3):353-358.
Authors:ZHANG Jing  WANG Jin-cheng  LIU Shu-shen  GE Hui-lin  LIU Hai-ling
Abstract:Ionic liquids(ILs)are a kind of novel green solvents designed to replace traditional volatile organic solvents.Due to their non-volatility,ILs have no such trend to pollute the air and they are widely used in industries.However,some ILs can dissolve in water,and they still have potential ecotoxicities.The toxicities of ILs themselves to organism have been reported in the literatures.However,the toxicity interaction between ILs and other pollutants coexisting in aquatic ecosystems has been poorly studied.An imidazole-type IL,C16H31ClN2(DMI),and a pesticide,dimethoate(DIM) were,therefore,selected as target compounds,and their individual toxicity and mixture toxicity were determined by the microplate toxicity analysis using Vibrio qinghaiensis sp.-Q67 as the indicator organism.To systemically examine the toxicity interaction between DMI and DIM with the different concentration compositions,five mixture rays were designed by a simplified central composite with the fixed concentration ratio ray(CCDray).The concentration addition and independent action models were used to predict and evaluate the toxicity interaction.Results showed that there was a significant antagonism between high concentration DMI and low concentration DIM while they are additive in other concentration compositions.
Keywords:C16H31ClN2
本文献已被 维普 万方数据 等数据库收录!
点击此处可从《生态毒理学报》浏览原始摘要信息
点击此处可从《生态毒理学报》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号