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农药混配制剂环境风险评估现状与展望
引用本文:陈朗,姜辉,贾俊超,曲甍甍,周艳明,周欣欣,黄健,沈燕,王友启,于雪骊.农药混配制剂环境风险评估现状与展望[J].生态毒理学报,2017,12(4):15-24.
作者姓名:陈朗  姜辉  贾俊超  曲甍甍  周艳明  周欣欣  黄健  沈燕  王友启  于雪骊
作者单位:1. 沈阳化工研究院安全评价中心,沈阳,110141;2. 农业部农药检定所,北京,100026;3. 中化作物保护品有限公司,上海,200125
基金项目:国家重点研发计划(2016YFD0300708-04);国家自然科学基金(21377139)
摘    要:本文综述了欧洲和美国农药混配制剂的环境风险评估方法。详细介绍了欧洲食品安全局(EFSA)评估体系中的2种方法,即,基础的"整体测试法"和近年来提倡的"基于组分的方法"。"基于组分的方法"的特点是以浓度加和模型(CA模型)作为默认假设进行初级评估,以独立作用模型(IA模型)等作为高级评估手段的农药混配制剂环境风险评估方法。此外,本文还介绍了模型偏差率(MDR)、毒性相似度及毒力单元(TU)等概念以及混配制剂风险评估流程。本文的目的旨在为建立我国农药混配制剂的环境风险评估方法体系提供参考。

关 键 词:农药混配制剂  整体测试法  基于组分的方法  浓度加和模型  毒力单元  毒性相似度
收稿时间:2017/5/27 0:00:00
修稿时间:2017/7/12 0:00:00

Environmental Risk Assessment for Mixed Pesticide Products:Current Situation and Prospects
Chen Lang,Jiang Hui,Jia Junchao,Qu Mengmeng,Zhou Yanming,Zhou Xinxin,Huang Jian,Shen Yan,Wang Youqi,Yu Xueli.Environmental Risk Assessment for Mixed Pesticide Products:Current Situation and Prospects[J].Asian Journal of Ecotoxicology,2017,12(4):15-24.
Authors:Chen Lang  Jiang Hui  Jia Junchao  Qu Mengmeng  Zhou Yanming  Zhou Xinxin  Huang Jian  Shen Yan  Wang Youqi  Yu Xueli
Institution:1.Safety Evaluation Center, Shenyang Research Institute of Chemical Industry, Shenyang 110141, China 2.Institute for the Control of Agrochemicals, Ministry of Agriculture, Beijing 100026, China 3.Sinochem International Crop Care Company Limited, Shanghai 200125, China
Abstract:We reviewed the environmental risk assessment methods for mixed pesticides products used in European and American in the paper. The two approaches of European Food Safety Authority (EFSA) risk evaluation system including"overall test method"and"component-based approaches"have been introduced in detail. The"component-based approaches"conduct first tier risk assessment for mixed pesticides products using the Concentration Addition (CA) model as reasonable default assumption, then finish higher tier risk assessment using Independent Action (IA) Model and Mixed Model (MM). In addition, the definition related to mixed pesticides products risk assessment inclu-ding model deviation ratio (MDR), toxicity similarity and toxicity unit have been described clearly. The purpose of the study is providing reference to environmental risk assessment or the mixed pesticide products in China.
Keywords:mixed pesticide products  overall test method  component-based approaches  concentration addition model  toxicity unit  toxicity similarity
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