| 邻苯二甲酸二乙基己酯(DEHP)毒理与健康效应研究 |
| |
| 引用本文： | 王佳,董四君.邻苯二甲酸二乙基己酯(DEHP)毒理与健康效应研究[J].生态毒理学报,2012,7(1):25-34. |
| |
| 作者姓名： | 王佳 董四君 |
| |
| 作者单位： | 中国科学院城市环境研究所,中国科学院城市环境与健康重点实验室,厦门,361021 |
| |
| 基金项目： | 中国科学院百人计划项目（KZCX2-YW-BR-18）；厦门市科技计划项目（3502Z20112019） |
| |
| 摘 要： | 邻苯二甲酸二乙基己酯(DEHP)作为重要的聚氯乙烯塑料增塑剂在工业上应用广泛。目前,DEHP在海洋、大气、饮用水及动植物体内均被不同程度检出,对生态环境造成日益严重的污染。结合国内外毒理学研究成果,概述DEHP的人体暴露及代谢途径;并从肝脏、心脏、生殖发育系统和呼吸系统等方面详细探讨DEHP对动物健康的危害及其可能的毒性机制,以及对人体健康潜在的影响;在此基础上,对目前存在的问题及进一步研究的方向进行了探讨和展望。
|
| 关 键 词： | 邻苯二甲酸二乙基己酯 生殖发育 呼吸系统 健康效应 |
| 收稿时间： | 6/7/2011 12:00:00 AM |
| 修稿时间： | 2011/7/23 0:00:00 |
Research Advances in Toxicology of DEHP and Its Health Effects |
| |
| Wang Jia and Dong Sijun.Research Advances in Toxicology of DEHP and Its Health Effects[J].Asian Journal of Ecotoxicology,2012,7(1):25-34. |
| |
| Authors: | Wang Jia and Dong Sijun |
| |
| Institution: | Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China;Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China |
| |
| Abstract: | As an important plasticizer for polyvinyl chloride plastics, DEHP was widely used in industry, which was currently detected in the ocean, air, drinking water, animals and plants to different extent. DEHP has caused ever-increasing ecological environment pollution. In this paper, the domestic and foreign toxicological researches were reviewed, which were related to the human exposure and metabolic pathways of DEHP. The toxicity and potential danger of DEHP to animals and human health were discussed in detail from the aspect of liver, heart, reproductive/developmental system and respiratory system. On these bases, the existing problems and further research directions were pointed out. |
| |
| Keywords: | DEHP reproductive development respiratory system health effect |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《生态毒理学报》浏览原始摘要信息 |
| 点击此处可从《生态毒理学报》下载免费的PDF全文 |
|
