理论毒理学研究进展

毒理学是近代发展起来的科学,由于工农业生产的迅速发展,化学物质剧增,迄今登记在册的化学物质已超过2 600万种,每年还新增2 000多种,因此传统的毒性鉴定已远远不能满足时代的要求,针对各种化学物质的细致的毒理学研究更是难以实现。因此毒理学必须在理论层面实现突破,缩短研究时间,减少研究经费及人力、物力的消耗,同时可使化学物质得到更安全的应用。另外,动物保护已列入议事日程,不再允许大量使用动物做毒理方面的实验,这些促进了理论毒理学的发展。

The Progress in Theoretical Toxicology

Toxicology is a modern science. Because of the rapid development of industry and agriculture, the amount of chemicals increases explosively. There has been more than 26 000 000 chemicals registered in the world, and over 2 000 new chemicals are produced every year. Therefore the traditional methods of toxicological evaluation cannot meet the requirements in the modern society, let alone the precise toxicological study for various chemicals. It is needed to make innovation in theory, so as to shorten the period, reduce the expenditure and input in the research, which may make the applications of chemicals safer. Meanwhile, as animal welfare is putting on the public's agenda, few animals will be permitted to be used largely in the toxicological research. All of these promote the development of theoretical toxicology.