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| 全氟烷基磺酸盐(PFOS)及其替代品对两栖类胚胎的发育毒性 | |
| 引用本文： | 任东凯,苏红巧,刘芃岩,韦荣国,秦占芬.全氟烷基磺酸盐(PFOS)及其替代品对两栖类胚胎的发育毒性[J].生态毒理学报,2012,7(5):561-564. |
| 作者姓名： | 任东凯 苏红巧 刘芃岩 韦荣国 秦占芬 |
| 作者单位： | 1. 河北大学化学与环境科学学院,保定071002;中国科学院生态环境研究中心,环境化学和生态毒理学国家重点实验室,北京100085 2. 中国科学院生态环境研究中心,环境化学和生态毒理学国家重点实验室,北京100085 3. 河北大学化学与环境科学学院,保定,071002 |
| 基金项目： | “863”计划课题(2010AA 065105)和环保公益专项(201109048) |
| 摘 要： | 用非洲爪蟾胚胎致畸实验和黑斑蛙胚胎发育毒性实验,比较研究了PFOS及其4种替代品对两栖动物胚胎的发育毒性。结果发现,用调聚法合成的织物三防整理剂和50%的全氟丁基有机铵盐阳离子表面活性剂同PFOS一样对非洲爪蟾胚胎有明显毒性,且织物三防整理剂和表面活性剂的毒性强于PFOS;电解氟化法合成的C4织物及C6织物三防整理剂(以下简称C4及C6织物三防整理剂)对非洲爪蟾胚胎没有明显毒性。与非洲爪蟾不同,PFOS和4种替代品对黑斑蛙胚胎没有明显毒性。结果显示,从生物安全性的角度分析,C4和C6织物三防整理剂可作为PFOS的替代品使用,而织物三防整理剂和表面活性剂的毒性比PFOS大,作为PFOS替代品使用需要慎重考虑。 |
| 关 键 词： | PFOS 替代品 非洲爪蟾 黑斑蛙 发育毒性 |
| 收稿时间： | 2012/6/30 0:00:00 |
| 修稿时间： | 9/8/2012 12:00:00 AM |
Developmental Toxicity of Perfluorooctane Sulfonate (PFOS) and Its Substitutes to Amphibian Embryos |
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| Ren Dongkai,Su Hongqiao,Liu Pengyan,Wei Rongguo and Qin Zhanfen.Developmental Toxicity of Perfluorooctane Sulfonate (PFOS) and Its Substitutes to Amphibian Embryos[J].Asian Journal of Ecotoxicology,2012,7(5):561-564. | |
| Authors: | Ren Dongkai Su Hongqiao Liu Pengyan Wei Rongguo and Qin Zhanfen |
| Institution: | 1. College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China 2. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China |
| Abstract: | In this study, the developmental toxicity of perfluorooctane sulfonate (PFOS) and its four substitutes on Xenopus laevis embryos and Rana nigromaculata embryos studied comparatively. It was found that tri-fabric finishing agent synthetized using telomerization method (tri-fabric finishing agent) and 50% perfluorobutyl organic ammonium salt cationic surfactant (50% cationic surfactants) as well as PFOS had obvious toxicity to X. laevis embryos. Moreover, the toxicity of tri-fabric finishing agent and 50% cationic surfactant was significantly higher than that of PFOS. C4 and C6 tri-proof finishing agent (C4 and C6) synthetized by electrolysis fluorination method were not toxic to X. laevis embryos. To R. nigromaculata embryos, PFOS and four substitutes had no obvious toxicity. In term of biological safety, these results show that C4 and C6 might be used as the substitutes for PFOS, while tri-fabric finishing agent and 50% cationic surfactant should be considered carefully. |
| Keywords: | PFOS substitutes Xenopus laevis Rana nigromaculata developmental toxicity |
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