| 多溴联苯醚在啮齿类动物体内的代谢动力学研究进展 |
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| 引用本文： | 王旭亮,何欢,杨绍贵,孙成.多溴联苯醚在啮齿类动物体内的代谢动力学研究进展[J].生态毒理学报,2011,6(1):1-8. |
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| 作者姓名： | 王旭亮 何欢 杨绍贵 孙成 |
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| 作者单位： | 污染控制与资源化研究国家重点实验室 南京大学环境学院 南京 210093;污染控制与资源化研究国家重点实验室 南京大学环境学院 南京 210094;污染控制与资源化研究国家重点实验室 南京大学环境学院 南京 210095;污染控制与资源化研究国家重点实验室 南京大学环境学院 南京 210096 |
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| 基金项目： | 国家重点基础研究发展计划(973)项目(NO. 2009CB421604) |
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| 摘 要： | 多溴联苯醚(PBDEs)是一类持久性有机污染物(POPs),其作为一种广泛使用的溴化阻燃剂在环境中普遍存在.PBDEs对生物体和人体存在内分泌干扰等毒性危害,正受到人们越来越多的关注.然而目前PBDEs对人体造成的影响都是由动物实验(主要是啮齿类动物)外推而得,因此研究不同的PBDEs同系物在啮齿类动物体内的代谢动力学...
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| 关 键 词： | 多溴联苯醚 啮齿类动物 体内 代谢动力学 |
| 收稿时间： | 2010/3/20 0:00:00 |
| 修稿时间： | 2010/5/31 0:00:00 |
Advance in Vivo Metabolic Kinetics of Polybrominated Diphenyl Ethers in Rodents |
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| Wang Xuliang,He Huan,Yang Shaogui and Sun Cheng.Advance in Vivo Metabolic Kinetics of Polybrominated Diphenyl Ethers in Rodents[J].Asian Journal of Ecotoxicology,2011,6(1):1-8. |
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| Authors: | Wang Xuliang He Huan Yang Shaogui and Sun Cheng |
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| Institution: | Wang Xuliang,He Huan,Yang Shaogui,Sun Cheng State Key Laboratory of Pollution Control and Resources Reuse,School of the Environment,Nanjing University,Nanjing 210093,China |
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| Abstract: | Polybrominated diphenyl ethers (PBDEs) are considered as one kind of persistent organic pollutants (POPs), which are ubiquitous in the environment due to their widely used as flame retardants. More and more attention has focused on their hazardous effects on organisms and human. At present, the extrapolation from animal experiments (mainly rodents), has been employed to evaluate the impacts of PBDEs to human. Therefore, it is important to study different PBDEs congeners in vivo metabolism kinetic parameters. This paper is an overview of absorption, distribution, metabolism and excretion of PBDEs in rodents in vivo. It should be useful for the scientists to carry out the related researches actively for assessing the risks to human health and environmental hazards. |
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| Keywords: | PBDEs rodents in vivo metabolic kinetics |
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