| 有机紫外防晒剂内分泌干扰效应研究进展 |
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| 引用本文： | 李立平,魏东斌,李敏,肖铭,阴俊霞,杜宇国.有机紫外防晒剂内分泌干扰效应研究进展[J].环境化学,2012,31(2):150-156. |
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| 作者姓名： | 李立平 魏东斌 李敏 肖铭 阴俊霞 杜宇国 |
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| 作者单位： | 环境化学与生态毒理学国家重点实验室,中国科学院生态环境研究中心,北京100085 |
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| 基金项目： | 国家自然科学基金项目(20877090,21077123);重点基金项目(50938004)资助 |
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| 摘 要： | 有机紫外防晒剂是一类新兴环境污染物,大量研究表明,部分有机紫外防晒剂能模拟生物体内多种激素的作用,干扰动物和人体正常的内分泌功能,造成严重的健康威胁.本文在大量文献调研的基础上,从个体水平、器官水平、细胞水平和分子水平4个层次,就有机紫外防晒剂对生殖系统、青春期发育、成活率、pS2蛋白、卵黄蛋白原及激素受体等多方面的影响进行了综述,以加深对紫外防晒剂的认识,也为紫外防晒剂的正确使用及相关部门对其进行科学管理提供参考.
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| 关 键 词： | 紫外防晒剂 内分泌干扰效应 生殖 卵黄蛋白原 激素受体 |
Review on endocrine disrupting effects of organic UV filters |
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| LI Liping WEI Dongbin LI Min XIAO Ming YIN Junxia DU Yuguo.Review on endocrine disrupting effects of organic UV filters[J].Environmental Chemistry,2012,31(2):150-156. |
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| Authors: | LI Liping WEI Dongbin LI Min XIAO Ming YIN Junxia DU Yuguo |
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| Institution: | LI Liping WEI Dongbin LI Min XIAO Ming YIN Junxia DU Yuguo(State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences,Beijing,100085,China) |
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| Abstract: | Organic ultraviolet filters(UV filters) are a class of emerging environmental contaminants.Plenty of research work discovered that some UV filters could simulate functions of endogenous hormones in organisms.Thus,organic UV filters would disturb the normal functions of endocrine glands and threaten health of animals and human beings.In the present review,the adverse endocrine effects of organic UV filters on reproductive organs,puberty,survival rate,protein pS2,vitellogenin(VTG),hormone receptors were summarized.The research will be helpful to provide references for reasonable use and scientific management of UV filters. |
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| Keywords: | UV filters endocrine disrupting effects reproductivity VTG hormone receptors |
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