| 分子生物标志物在污染环境早期诊断和生态风险评价中的应用 |
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| 引用本文： | 王晓蓉,罗义,施华宏,张景飞. 分子生物标志物在污染环境早期诊断和生态风险评价中的应用[J]. 环境化学, 2006, 25(3): 320-325 |
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| 作者姓名： | 王晓蓉 罗义 施华宏 张景飞 |
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| 作者单位： | 南京大学环境学院,污染控制与资源化研究国家重点实验室,南京,210093;南京大学环境学院,污染控制与资源化研究国家重点实验室,南京,210093;南京大学环境学院,污染控制与资源化研究国家重点实验室,南京,210093;南京大学环境学院,污染控制与资源化研究国家重点实验室,南京,210093 |
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| 基金项目： | 中国科学院资助项目 , 科技部科研项目 |
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| 摘 要： | 介绍了抗氧化防御系统、应激蛋白HSP70、活性氧(ROS)以及植络素(PCs)等作为分子水平上的生物标志物,在水和土壤环境污染早期诊断和生态风险评价中的研究现状及最新进展,以及污染物胁迫下活性氧的产生及对机体的氧化损伤机理,并展望了分子生物标志物在污染环境早期诊断和生态风险评价中的发展方向.
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| 关 键 词： | 生物标志物 抗氧化防御系统 应激蛋白 活性氧 植络素 |
APPLICATION OF MOLECULAR BIOMARKERS IN EARLY DIAGNOSIS AND ECOLOGICAL RISK ASSESSMENT FOR WATER AND SOIL |
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| WANG Xiao-rong,LUO Yi,SHI Hua-hong,ZHANG Jing-fei. APPLICATION OF MOLECULAR BIOMARKERS IN EARLY DIAGNOSIS AND ECOLOGICAL RISK ASSESSMENT FOR WATER AND SOIL[J]. Environmental Chemistry, 2006, 25(3): 320-325 |
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| Authors: | WANG Xiao-rong LUO Yi SHI Hua-hong ZHANG Jing-fei |
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| Affiliation: | State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Najing, 210008, China |
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| Abstract: | Molecular biomarkers due to their sensitivities in early warning to indicate biological damages following the long-term exposure with low concentrations of the pollutants,have been wildly used in ecological risk assessment of water and soil compartments,and are becoming one of the hotspots in ecotoxicological studies.In this paper,the overview studies and the most advancing developments in antioxidant defense,HSP70,reactive(oxygen) species(ROS),phytochelatins(PCs)which are used as the molecular biomarkers in early diagnosis and ecological risk assessment in water and soil are reviewed,as well as the mechanisms of ROS generation and it mediated oxidative damage.Finally,perspectives of trends in molecular biomarkers in early diagnosis and ecological risk assessment are discussed. |
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| Keywords: | biomarker antioxidant defense HSP70 ROS phytochelatins. |
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